Investigation of the Influence of the Human Microbiome on the Pathogenesis and Recurrence Probability in Giant Cell Arteritis
Status: Recruiting
Location: See all (2) locations...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY
The longitudinal observational study aims to assess the impact of the microbiome especially the gut-microbiome in the emergence and course of giant cell arteritis (abbr. GCA) patients. At diagnosis and 6 month follow up we will analyze the oral, blood and gut microbiome from GCA patients and healthy controls. Thereby identified potential candidate biota will be further analyzed for possible interactions and influence on the immune system.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:
• • Diagnosis of Giant cell arteritis (only in one arm)
Locations
Other Locations
Germany
Clinic of Internal Medicine III, Department of Oncology, Haematology, Rheumatology and Clinical Immunology, University Hospital Bonn
RECRUITING
Bonn
University Hospital Bonn
RECRUITING
Bonn
Time Frame
Start Date: 2024-02-29
Estimated Completion Date: 2028-02
Participants
Target number of participants: 50
Treatments
GCA Patients
Primary diagnosis of giant cell arteritis
Control
Control group without rheumatologic disease
Related Therapeutic Areas
Sponsors
Leads: University of Bonn